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As per available reports about 43 relevant Journals, 38 Conferences, 5 Workshops are presently dedicated exclusively to bioanalytical methods and about 335 articles are being published on bioanalytical methods.
Bioanalytical Method is quantitative determination of drugs and their metabolites in biological fluids are crucial during drug discovery and development. It is the preferred methodology for that purpose. The focus of bio analysis in the pharmaceutical industry is to provide a quantitative measure of the active drug and/or its metabolite(s) for the purpose of pharmacokinetics, bioequivalence and exposure–response.
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Scope and Importance:
Bioanalytical methodology Conference provides the scope for opportunities to learn progressed by international scientists and academicians. So many symposiums have been conducted and are to be organized all across the globe focusing on the significance of Bio analytical Innovations, Therapeutic Possibilities and Technological Challenges is going to be organized which will focus on Bio analysis
Bioanalytical methodology is a sub-discipline of analytical chemistry covering the quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and biotics (macromolecules, proteins, DNA, large molecule drugs, metabolites) in biological systems.
The main characteristics of a bioanalytical method that are essential to ensure the acceptability of the performance and the reliability of analytical results are: selectivity, lower limit of quantification, the response function and calibration range (calibration curve performance), accuracy, precision, matrix effects, stability of the analyte(s) in the biological matrix and stability of the analyte(s) and of the internal standard in the stock and working solutions and in extracts under the entire period of storage and processing conditions.
When mass-spectrometry (MS) detection is used in the bioanalytical method, a stable isotope-labelled IS is recommended to be used whenever possible. However, it is essential that the labelled standard is of the highest isotope purity and that no isotope exchange reaction occurs. The presence of any unlabelled analyte should be checked and if relative amounts of unlabelled analyte are detected the potential influence has to be evaluated during method validation.
Market Analysis:
The global market for bioanalytical development of drugs reached nearly $39.5 billion and $46.5 billion in 2013 and 2014, respectively. This market is expected to grow at a compound annual growth rate (CAGR) of 11.3% to nearly $79.5 billion for the period 2014-2019.
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This page was last updated on November 5, 2024
