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Shingles, also called herpes zoster or zona like skin eruptions that may occur on the trunk of the body. The virus that causes chickenpox, the varicella zoster virus(VSV), can becomedormant in nerve cells after an episode of chickenpox and later reemerge as shingles. Initially, red patches of rash develop into blisters. Because the virus travels along the nerve to the skin, it can damage the nerve and cause it to become inflamed. This condition can be verypainful. If the pain persists long after the rash disappears, it is known as postherpetic neuralgia Herpes zoster (or simply zoster), commonly known as shingles and also known as zona, is a viral characterized by a painful skin rash with blisters in a limited area on one side of the body (left or right), often in a stripe..After the initial episode of chickenpox resolves, the varicella zoster virus remains latent in the nerve cell bodies and, less frequently, the non-neuronal satellite cells of the dorsal root, cranial nerve or autonomic ganglia without causing any symptoms. Throughout the world, the incidence rate of herpes zoster every year ranges from 1.2 to 3.4 cases per 1,000 healthy individuals, increasing to 3.9–11.8 per year per 1,000 individuals among those older than 65 years. Over a lifetime, a large fraction of people develop herpes zoster, though usually only once; a 1965 16-year British study proposed that, of those individuals living to age 85, 50% would likely have had at least one attack, and 1% had at least two attacks. The zoster (shingles) vaccine is considered the most effective way to reduce incidence of herpes zoster and post herpetic neuralgia, and to reduce severity of any outbreak Antiviral drug treatment is considered a second-line approach, but can reduce the severity and duration of herpes zoster if a seven- to ten-day course of these drugs is started within 72 hours of the appearance of the characteristic rash.
Treatment
Shingles almost always resolves spontaneously and may not require any treatment except for the relief of symptoms. In most people, the condition clears on its own in one or two week sand seldom recurs.Cool, wet compresses may help reduce pain. If there are blisters or crusting, applying compresses made with diluted vinegar will make the patient more comfortable.
Corticosteroids, in combination with antiviral therapy, also are used to treat severe infections, such as those affecting the eyes,and to reduce severe pain.Once the blisters are healed, some people continue to experience pain for months or even years (postherpetic neuralgia). This pain can be excruciating. Consequently, the doctor may prescribe tranquilizers, sedatives, or antidepressants to be taken at night. As noted aboveattempts to treat postherpetic neuralgia with the antiviral drug famciclovir have shown somepromising results. When all else fails, severe pain may require a permanent nerve block. A newer medication to treat postherpectic neuralgia is pregabalin, to be marketed in theUnited States under the trade name Lyrica. Pregabalin was approved by the Food and Drug Administration in September 2004 for the treatment of diabetic neuropathy as well aspostherpetic neuralgia. The drug has been shown to improve patients' sleep and overall quality of life as well as relieve pain. Its most common side effects are drowsiness, headache, dry mouth, and dizziness.
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CONFERENCES.
Solar Shingles conferences and events.
2013 National Conference - The Gospel Coalition.
ANA Annual Conference.
SJRMC UCEM Residency Conferences.
NASSP 2013 National Conference.
SBSA academic conferences in the United States.
Annual AAEM Scientific Assembly.
NRCA, National Conference.
CME Conferences on Shingles.
IEEE International Conference.
MCOA 2012 Conference - Massachusetts Councils on Agi.
Societies.
National institute of allergy and infectious disease (NIAID).
vs. (varicella-zoster virus) research foundation.
The National Foundation for Infectious.
Technology Student Association Florida.
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This page was last updated on November 19, 2024
