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As per available reports about, 37 Relevant Journals, 54 Conferences, 12 Workshops are presently dedicated exclusively to Paddle dissolution and about 43 articles are being published on Paddle dissolution.
Paddle Dissolution: An API has to get dissolved in the physiological solution from the prepared dosage form in order to show its therapeutic effect. It is a crucial initial step when medicinal products are administered in the form of tablets and capsules. Rate of dissolution is a crucial aspect of a drug as it specifies how quickly the drug in a formulation is discharged in the body and made accessible for absorption.
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Scope and Importance:
In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. In vitro drug dissolution data generated from dissolution testing experiments can be related to in vivo pharmacokinetic data by means of in vitro-in vivo correlations (IVIVC). A well established predictive IVIVC model can be very helpful for drug formulation design and post-approval manufacturing changes.
Paddle Dissolution: An API has to get dissolved in the physiological solution from the prepared dosage form in order to show its therapeutic effect. It is a crucial initial step when medicinal products are administered in the form of tablets and capsules. Rate of dissolution is a crucial aspect of a drug as it specifies how quickly the drug in a formulation is discharged in the body and made accessible for absorption.
There are 2 main methods, Basket type, Paddle Type
In paddle type, the design of the paddle and the speed at which it rotates are important. The paddle must rotate smoothly with no staggering and no whirlpool should form when the paddle is turning tablets or capsule is allowed to sink to the bottom of the vessel before the paddle starts rotating.
Market Analysis:
The global market for mining chemicals was valued at $19.4 billion in 2013 and increased to $20.7 billion in 2014. The market is expected to reach $28.5 billion by 2019, with a compound annual growth rate (CAGR) of 6.6% from 2014 to 2019.
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This page was last updated on November 6, 2024
