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As per available reports about 39 relevant journals, 171 Conference Proceedings, 11 conferences are presently dedicated exclusively to protein kinase.
Protein Kinases modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. They are key regulators of cell function that constitute one of the largest and most functionally diverse gene families. The human genome contains about 500 protein kinase genes and they constitute about 2% of all human genes. By adding phosphate groups to substrate proteins, they direct the activity, localization and overall function of many proteins, and serve to orchestrate the activity of almost all cellular processes.
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Scope and Importance
Kinases are particularly prominent in signal transduction and co-ordination of complex functions such as the cell cycle. The diversity of essential functions mediated by kinases is shown by the conservation of some 50 distinct kinase families between yeast, invertebrate and mammalian kinomes. These can be clustered into groups, families and sub-families, of increasing sequence similarity and biochemical function. Most kinases act on both serine and threonine (serine/threonine kinases), others act on tyrosine, and a number act on all three. The kinase dendrograms show the sequence similarity between these catalytic domains: the distance along the branches between two kinases is proportional to the divergence between their sequences.
Market Analysis
Protein crystallization is the most crucial and the largest segment, and it accounted for 47% of the market in 2013. On the basis of products, the protein crystallization market has segments such as reagents/consumables and instruments. Reagents/consumables accounted for 85% of the protein crystallization & crystallography product market. It is expected to grow at a high CAGR of 11% over the forecast period. The global market was valued at $775 million in 2013 and is expected to reach $1,253 million by 2018.
Seven major groups are labeled and colored distinctly. For instance, the tyrosine kinases form a distinct group, whose members phosphorylate proteins on tyrosine residues, whereas enzymes in all other groups phosphorylate primarily serine and threonine residues. Most kinases act on both serine and threonine, others act on tyrosine, and a number act on all three. The relationships shown on the tree can in some instances be used to predict protein substrates and biological function for many of the over 100 uncharacterized kinases presented here. A further 40 ‘atypical’ kinases have no sequence similarity to typical kinases, but are known or predicted to have enzymatic activity, and some are predicted to have a similar structural fold to typical kinases.
List of Best International Conferences
1. Nuclic Acids Conference
Aug 4-6, 2016 Seattle, USA
2. Synthetic Biology Conference
September 28-30, 2015 Houston, USA
3. Protein Engineering Conference
October 26-28, 2015 Chicago, USA
4. Clinical And Molecular Genetics Conference
November 28-30, 2016 Chicago, USA
5. 2nd Transcriptomics Conference
August 15-17, 2016 Portland, USA
6. 3rd Genomics & Pharmacogenomics Conference
September 21-23, 2015 San Antonio, USA
7. 3rd Clinical Pharmacy Conference
December 07-09, 2015 Atlanta, USA
8. 4th Integrative Biology Conference
June 13-15, 2016 Berlin, Germany
9. 4th Clinical Microbiology and Microbial Genomics Conference
October 05-07, 2015 Philadelphia, USA
10. 5th Computational Systems Biology Conference
August 22-23, 2016 Philadelphia, USA
11. 5th Metabolomics Conference
May 16-18, 2016 Osaka, Japan
12. 6th Metabolomics Conference
November 28-30, 2016 Florida, USA
13. 6th Proteomics Conference
March 29-30, 2016 Atlanta, USA
14. 6th Bioinformatics Conference
March 29-30, 2016 Valencia, Spain
15. 7th Proteomics Conference
October 10-12, 2016 Rome, Italy
16. EMBO Practical Course to Targeted proteomics: Experimental design and data analysis
September 28 to October 03, 2014 Barcelona, Spain
17. HUPO 2015 to HUPO 14th Annual World Congress
Septemebr 26-30, 2015 Vancouver, Canada
Related Societies and Associations
1. American Society for mass Spectrometry
2. Austrian Proteomics Society
3. American Electrophoresis Society
4. British Mass Spectrometry Society
5. California Separation Science Society
6. Canadian Mass Spectrometry Society
7. Danish Mass Spectrometry Society
8. European Proteomics Association
9. US Human Proteome Organization
10. Proteomics and Electrophoresis Societies
11. Spanish Proteomics Society– (Seprot)
12. Netherlands Proteomic Platform (Npp)
13. Japan Human Proteome Organisation (Jhupo)
14. Italian Proteomic Association (Itpa)
15. Portugese Proteomic Association (Rede Procura)
16. Iranian Proteomic Society
17. Taiwan Proteomic Society (Tps)
18. Human Proteome Organization
19. Italian Proteomics Association
20. Portuguese Proteomics Association
Related Companies
1. Caprion Proteomics
2. Applied Proteomics, Inc.
3. Proxeon
4. PTM Biolabs Inc
5. Biotech Support Group
6. BiognoSYS AG
7. GeneCopoeia
8. Sera Proteomics
9. Protein Metrics Inc.
10. MRM Proteomics Inc.
11. Agilent Technologies
12. Danaher
13. Thermo Fischer Scientific
14. Ab Sciex
15. Abbott Laboratories
16. Affymetrix
17. Ams Biotechnology
18. Avacta Life Sciences
19. Bd Biosciences
20. Biocompare
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This page was last updated on December 23, 2024
