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As per available reports about 17 Open Access articles, 43 Scientific conference Proceedings , 6 National symposiums and 22 speakers, 26 Editors, 1 Journal on Key word Immunoglobulins in Global Events page. Global Events of Conference series are presently dedicated exclusively to Antibodies and about 2000 articles are being published on Antibodies.
Immunoglobulins
Immunoglobulins are also known as antibodies. These are glycoprotein molecules which are produced by plasma cells (i.e) white blood cells. They act as critical part of the immune response by specifically recognizing and binding to particular antigens, such as bacteria or viruses and resulting in their destruction. The antibody immune response is highly complex and immensely specific. The various immunoglobulin isotypes differ in their biological features, structure, target specificity and distribution. Hence the assessment of the immunoglobulin isotype can provide useful insight into complex humoral immune response. Immunoglobulins are categorized into two. They are soluble antibodies and membrane-bound antibodies. Membrane-bound immunoglobulins are associated non-covalently with two accessory peptides forming the B-cell antigen receptor complex. IgM and IgD are the first antigen receptors expressed by B cells. The receptor is a prototype of the antibody that the B cell is prepared to produce. The B cell receptor (BCR) can only bind antigens. It is the heterodimer of Ig alpha and Ig beta that allows the cell to transduce the signal and respond to the presence of antigens on the cell surface. The signal generated causes the growth and proliferation of the B cell and antibody production inside the plasma cell. The general functions of immunoglobulins are Antigen binding and Effector functions. In case of Antigen binding these immunoglobulins bind specifically to one or a few closely related antigens. Each immunoglobulin actually binds to a specific antigenic determinant. The primary function is Antigen binding by antibodies resulting in protection of the host. The valency of antibody is the number of antigenic determinants that an individual antibody molecule can bind. The valency of all antibodies is at least two and in some cases more. Frequent binding of an antibody to an antigen has no direct biological effect. Preferably, these significant biological effects are the results of secondary "effector functions" of antibodies. The ability to carry out a particular effector function requires the antibody to bind to its antigen. Every immunoglobulin will not mediate all effector functions and if they mediate then such effector functions include Fixation of complement resulting in lysis of cells and the release of biologically active molecules and Binding to various cell types such as Phagocytic cells, lymphocytes, platelets, mast cells.
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Relevant Conferences on Antibodies
International Allergy Conference
March 29-30, 2016 Valencia, Spain
2nd Congress on Neuroimmunology and Therapeutics
March 31-April 02, 2016Atlanta, USA
Conference on Cancer Immunology and Immunotherapy
July 28-30, 2016Melbourne, Australia
6th Euro Virology Congress
March 10-12, 2016, Madrid, Spain
2nd Conference on Respiratory and Pulmonary Medicine
May 09-10, 2016Chicago, USA
2nd Conference on Innate Immunity
July 21-22, 2016 Berlin, Germany
2nd Conference on Parasitology
August 01-03, 2016Manchester, UK
5th Conference on Immunology
October 24-26, 2016Chicago, USA
2nd Conference on Influenza
September 12-14, 2016Berlin, Germany
10th Euro Global Summit on Vaccines & Vaccination
June 16-18, 2016Rome, Italy
Conference on Hepatitis Vaccines
June 16-18, 2016Philadelphia, USA
11th Global Summit on Vaccines & Vaccination
September 12-14, 2016Seattle, USA
12th Global Vaccines & Vaccination Summit and Expo
October 20-22, 2016Dubai, UAE
13th Asia Pacific Global Summit on Vaccines & Vaccination
November 10-12, 2016Brisbane, Australia
Antibody Biology & Engineering
March 20-25, 2016Galveston, TX
Proteins and Antibodies Congress
April 18-19, 2016 London, UK
8th Annual International Congress of Antibodies
April 25-28, 2016 Dalian, China
Cell Culture Engineering XV
May 8-13, 2016 California, USA
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This page was last updated on December 23, 2024
