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As per available reports about 2 relevant journals, 1 Conferences, 1 workshops are presently dedicated exclusively to under venom immunotherapy and about 2,070 articles are being published on under venom immunotherapy.
1. Insect venom immunotherapy (VIT) is the injection, under the skin, of gradually incrementing doses of insect venom. VIT commences with a minutely minuscular dose that is gradually incremented. This process causes a transmutation in how the immune system responds to the venom.
2. There is a high caliber of scientific evidence to show that VIT obviates rigorous allergic reactions (anaphylaxis) to insect stings, with the aim of obviating morbidity and death. More than 30 years experience has perceived it to be efficacious, well abode, safe when administered in opportune settings and associated with an amelioration in quality of life for patients.
3. Different insect venoms are associated with different risks of allergic reaction to the VIT injections themselves. In this regard, Jack Jumper Ant (JJA) VIT appears to be kindred to honeybee VIT.
4. Any clinical accommodation that is competent to distribute honeybee VIT is additionally competent to distribute JJA VIT. The same protocols used to administer honeybee VIT can be applied to JJA VIT.
5. The protocols of administration associated with the lowest risks of allergic reactions to VIT are the more gradual outpatient ("conventional" and "semirush") approaches.
6. Expedited inpatient approaches ("rush" and "ultrarush") may be utilized, but these present higher risks of allergic reactions. Patients offered expedited inpatient treatment should be conscientiously culled so as to omit those at greatest risk of decompensating during a reaction.
7. There is a jeopardy of allergic reactions to VIT injections. Emergency procedures and experience with treating anaphylaxis must be in place for the treatment of these reactions. This applies to all forms of injection immunotherapy, not just JJA VIT.
8. JJA VIT is unique because the JJA is found only in Australia. The number of patients affected on a worldwide substratum is therefore minute. This presents a quandary for the manufacture and supply of venom extract because there is no “economy of scale”.
9. At present, JJA venom is only available as an Active Pharmaceutical Ingredient (API), i.e. in concentrated form. This restricts its use to allergy accommodations that are able to manage formulation, storage and dispensing on-site.
10. Where there are constrained resources for providing JJA VIT, allergy accommodations should prioritise available treatment places for patients that (i) have had documented hypotensive or hypoxaemic reactions requiring emergency medical treatment, and (ii) have an perpetual risk of fortuitous stings.
Hymenoptera venom allergy is an immunoglobulin E (IgE)- mediated hypersensitivity to the venom of insects in the insect order Hymenoptera. This allergic reaction may be caused by stings from a number of species in this insect order, occurring only in epersons who have previously been sensitized to Hymenoptera venom
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Global allergy diagnostic and treatment of undervenom immunotherapy market is projected to increase to nearly $35.3 billion by 2015 from $31.5 billion in 2014. This market is expected to reach $46.8 billion by 2020, corresponding to a compound annual growth rate (CAGR) of 5.8% during 2015 to 2020 period.
Socities :
• Vaccination Clinics - Humane Society of Broward County
• Vaccine Clinics - Connecticut Humane Society
• Vaccine Clinics | Wisconsin Humane Society
• Australian Vaccinologists society
• The american Vaccines and vaccination society.
• US Immunology society.
• World immunization Association
• American Immunologists association.
• North California medical society
Companies :
• RMS MS Contin
• Endo Pharmaceuticals
• Carbex.
• Benforce M
• Minitide
• Reglide
• Rezult.
• Zolmelis
• Jalra
• Chromet
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This page was last updated on November 22, 2024
